- September 22, 0066 Emperor Nero creates the legion I Italica.
- September 22, 1236 The Lithuanians and Semigallians defeat the Livonian Brothers of the Sword in Battle of iauliai.
- September 22, 1499 Switzerland became an independent state.
- September 22, 1586 The battle of Zutphen occurs.
- September 22, 1598 Ben Jonson is indicted for manslaughter.
- September 22, 1656 All female jury hears case of woman who killed her child (acquit her)
- September 22, 1692 Last people hanged for witchcraft in the United States.
- September 22, 1692 Last person hanged for witchcraft in US
- September 22, 1756 Nassau Hall opens at Princeton University
- September 22, 1776 “American patriot, captain Nathan Hale executed for spying”
- September 22, 1776 Nathan Hale is hanged for spying during American Revolution.
- September 22, 1784 “Russia establishes a colony at Kodiak, Alaska.”
- September 22, 1784 “Russian trappers established a colony on Kodiak Island, AK”
- September 22, 1789 Office of Postmaster General of the US established by Congress
- September 22, 1789 The position of United States Postmaster General established.
- September 22, 1791 “Michael Faraday (chemist, physicist) born”
- September 22, 1792 Origin of French Republican Era
- September 22, 1792 primidi Vendmiaire of year 1 of the French Republican Calendar
- September 22, 1792 primidi Vendémiaire of year 1 of the French Republican Calendar
- September 22, 1817 John Quincy Adams becomes secretary of State
- September 22, 1823 “Joseph Smith, Jr. stated that he was directed by God through the Angel Moroni to the place where the Golden plates were stored.”
- September 22, 1851 “The city of Des Moines, Iowa was incorporated as Fort Des Moines.”
- September 22, 1862 Slavery in the United States: A preliminary version of the Emancipation Proclamation is released.
- September 22, 1863 President Lincoln makes his Emancipation Proclamation speech
- September 22, 1866 Decisive battle of Curupaity in the War of the Triple Alliance.
- September 22, 1868 Race riots in New Orleans La
- September 22, 1869 Richard Wagner’s opera Das Rheingold debuts in Munich.
- September 22, 1869 “The opera “”Das Rheingold”” is produced (Munich)”
- September 22, 1885 “Lord Randolph Churchill makes a speech in Ulster in opposition to Home Rule e.g. “”Ulster will fight and Ulster will be right””.”
- September 22, 1888 The first issue of National Geographic Magazine is published
- September 22, 1893 “The first American-built automobile, built by the Duryea Brothers, is displayed.”
- September 22, 1896 Queen Victoria surpasses her grandfather King George III as the longest reigning monarch in British history.
- September 22, 1903 Italo Marchiony granted patent for the ice cream cone
- September 22, 1908 The independence of Bulgaria is recognised.
- September 22, 1910 “The Duke of York’s Cinema opened in Brighton. It is still operating today, making it the oldest continually operating cinema in Britain.”
- September 22, 1911 “Cy Young at 44, wins his 511th & final game”
- September 22, 1914 “German U-Boat, the U-9, sunk three British cruisers in the North Sea”
- September 22, 1915 Southern Methodist University (Dallas Texas) holds its first class
- September 22, 1919 Steel strike begins in US
- September 22, 1927 “Famous “”Long count”” fight (Dempsey loses boxing title to Tunney)”